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姓名:盛彬彬 讲师,理学博士,硕士生导师 主要科研方向 微生物菌群分析、生物传感器、微生物和酶的基础及应用研究 联系方式 通讯地址:广东省广州市番禺区大学城外环东路280号基础医学院504, 邮编:510006,邮箱:shengbb@gdpu.edu.cn;binbinsdu@126.com |
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简介
盛彬彬,博士,讲师,硕士研究生导师,广东药科大学基础医学院病原生物学与免疫学系教师,广东药科大学第五层次引进人才。主要从事微生物和酶的基础及应用研究,主讲《微生物学与免疫学》、《医学免疫学》、《微生物学》等本科课程。2015年12月博士毕业于山东大学微生物国家重点实验室微生物学专业,后至中山大学从事博士后研究工作,于2019年6月作为第五层次人才引进至广东药科大学任教学科研岗教师。先后主持国家自然科学基金青年项目、中国博士后科学基金特别资助项目、广东省教育厅普通高校特色创新项目、广州市科学技术局基础与应用基础研究专题项目、广东省医学科学技术研究基金项目等5项科研项目,主持广东药科大学高等教育教学改革项目1项,指导省级大学生创新创业计划项目1项。在Chemical Engineering Journal、Applied and Environmental Microbiology、Environmental Science & Technology 、Water Research、Science of the Total Environment、Frontiers of Environmental Science & Engineering等SCI期刊发表科研论文20余篇,其中以第一作者或通讯作者发表科研论文11篇;发表教改论文2篇,其中以第一作者在中文核心期刊发表教改论文1篇。
教育背景及工作经历
2006-2010 山东大学生命科学院生物技术专业 本科 理学学士;
2010-2015 山东大学微生物技术国家重点实验室微生物学专业 研究生 理学博士;
2016-2019 中山大学环境科学与工程学院 博士后;
2019-至今 广东药科大学基础医学院病原生物与免疫学系 讲师
奖项及荣誉
2019 指导本科生获生命科学与生物制药学院“创新创业大赛”优胜奖 (指导教师)
2020 生命科学与生物制药学院“青年教师教学竞赛”二等奖
2024 指导研究生获“共享杯”科技资源共享服务创新大赛第二届粤港澳大湾区分赛优秀奖(指导教师)
2024 指导研究生获2024年度广东药科大学研究生学术论坛“研究生学术之星”(指导教师)
2022 广东药科大学生命科学与生物制药学院“优秀青年教师”
2022/ 2023 获院级民主评议“优秀党员”
2023 广东药科大学基础医学院“优秀共产党员”
2023 广东药科大学基础医学院“师德标兵”
2023 广东药科大学基础医学院“优秀教育工作者”
2023 广东药科大学“优秀教师团队”成员
承担科研课题
1. MBR中多糖降解细菌的关键酶识别与分子改造及其对膜污染的控制机制,国家自然科学基金委青年科学基金项(21607177,2017.01-2019.12),20万元,已结题,主持
2. 微生物视角解析ANAMMOX颗粒污泥颗粒增大与上浮机制,中国博士后基金委第11批中国博士后科学基金特别资助项目(2018T110910,2018.01-2019.01),15万元,已结题,主持
3. 广东药科大学第五层次人才引进启动经费项目,广东药科大学(2019.11-2024.11),20万,已结题,主持
4. 新型D-乳酸氧化酶制备生物传感器的应用基础研究,广东省教育厅普通高校特色创新项目(自然科学)(2019KTSCX070,2020.01-2024.12),5万元,在研,主持
5. 基于D-乳酸氧化酶构建介体型D-乳酸生物传感器最适电子介体和固载方法的研究与应用,广州市科学技术局基础与应用基础研究专题项目(202201010516,2022.04.01-2025.03.31),5万元,在研,主持
6. 基于 D-乳酸氧化酶与纳米材料修饰的 DET 型 D-乳酸生物传感器的研究,广东省卫生健康委员会广东省医学科学技术研究基金项目(A2023454,2023.07.01-2025.06.30),1万元(自筹0.5万元),在研,主持
科研论文
(1) Binbin Sheng# *, Shitong Liu#, Kenan Xiong, Jiaming Liu, Shang Zhu, Rongxin Zhang*. Microbial community dynamics in different floc size aggregates during nitrogen removal process upgrading in a full-scale landfill leachate treatment plant. Bioresource Technology, 2024, 413: 131484. (一区,IF 9.7)
(2) Shingtong Liu#, Yixin Liang#, Binbin Sheng*, Rongxin Zhang*. Multiple sclerosis and COVID-19: a bidirectional Mendelian randomization study. Frontiers in Immunology, 2024, 15: 1451347.(*并列通讯,二区,IF 5.7)
(3) Binbin Sheng, Depeng Wang, Xianrong Liu, Guangxing Yang, Wu Zeng, Yiqing Yang, Fangang Meng*. Taxonomic and functional variations in the microbial community during the upgrade process of a full-scale landfill leachate treatment plant — from conventional to partial nitrification-denitrification. Frontiers of Environmental Science & Engineering, 2020, 14: 1-12. (一作,二区,IF 4.357)
(4) Junshi Tao, Jiali Xing, Depeng Wang, Binbin Sheng*, Fangang Meng. Deciphering the genesis of anammox granular sludge floating from the perspective of microbial community. Journal of Water Process Engineering, 2020, 36: 101265. (通讯作者,二区,IF 5.485)
(5) Binbin Sheng, Haiying Cong, Shaoqing Zhang, Fangang Meng*. Interactive effects of tetracycline and nitrosifying sludge microbiota in a nitritation membrane bioreactor. Chemical Engineering Journal, 2018, 341: 556-564 (一区,IF 6.735)
(6) Shaoqing Zhang#, Binbin Sheng#, Wenting Lin, Fangang Meng*. Day/night temperature differences (DNTD) trigger changes in nutrient removal and functional bacteria in membrane bioreactors. Science of the Total Environment, 2018, 636: 1202-1210(#并列一作,二区,IF 4.610)
(7) Raju Naga Maddela#, Binbin Sheng#, Shasha Yuan, Zhongbo Zhou, Ronald Villamar-Torres, Fangang Meng*. Roles of quorum sensing in biological wastewater treatment: A critical review. Chemosphere, 2019, 221: 616-629(#并列一作,二区,IF 4.427)
(8) Binbin Sheng, Jing Xu, Yongsheng Ge, Shuo Zhang, Danqi Wang, Chao Gao*, Cuiqing Ma, Ping Xu. Enzymatic resolution by a d-lactate oxidase catalyzed reaction for (S)-2-hydroxycarboxylic acids. ChemCatChem, 2016, 8(16): 2630-2633(二区,IF 4.674)
(9) Binbin Sheng, Jing Xu, Yingxin Zhang, Tianyi Jiang, Sisi Deng, Jian Kong, Chao Gao*, Cuiqing Ma, Ping Xu. Utilization of d-lactate as an energy source supports the growth of Gluconobacter oxydans, Applied and Environmental Microbiology, 2015, 81(12): 4098-4110 (微生物权威期刊,二区,IF 3.633)
(10) Binbin Sheng, Zhaojuan Zheng, Min Lv, Haiwei Zhang, Tong Qin, Chao Gao*, Cuiqing Ma, Ping Xu. Efficient production of (R)-2-hydroxy-4-phenylbutyric acid by using a coupled reconstructed d-lactate dehydrogenase and formate dehydrogenase system, PloS One, 2014, 9(8), e104204(三区,IF 2.766)
(11) Binbin Sheng#, Jun Ni#, Chao Gao, Cuiqing Ma*, Ping Xu. Draft genome sequence of the Gluconobacter oxydans strain DSM 2003, an important biocatalyst for industrial use. Genome Announcements, 2014, 2(2): e00417-14.
(12) 曾琳#, 叶小婷#, 叶芷韵, 何宏栩, 盛彬彬*(通讯作者). 肿瘤微环境的乳酸代谢与监测. 癌症进展, 2024, 22: 1868-1871.
(13) Shuang Zhu*, Zhijie Tan, Ziyu Guo, Huijian Zheng, Baoshan Zhang, Zhi Qin, Junting Xie, Yuexia Lin, Binbin Sheng, Guanglei Qiu, Sergei Preis, Chaohai Wei*. Symbiotic virus-bacteria interactions in biological treatment of coking wastewater manipulating bacterial physiological activities. Water Research, 2024, 257: 121741.
(14) Yabing Meng, Binbin Sheng, Fangang Meng*. Changes in nitrogen removal and microbiota of anammox biofilm reactors under tetracycline stress at environmentally and industrially relevant concentrations. Science of the Total Environment, 2019, 668: 379-388.
(15) Zijian Chen, Yabing Meng, Binbin Sheng, Zhongbo Zhou, Chao Jin, Fangang Meng*. Linking exoproteome function and structure to anammox biofilm development. Environmental Science & Technology, 2019, 53: 1490-1500.
(16) Zhong Li, Manman Zhang, Tongtong Jiang, Binbin Sheng, Cuiqing Ma, Ping Xu, Chao Gao*, Enzymatic cascades for efficient biotransformation of racemic lactate derived from corn steep water, ACS Sustainable Chemistry & Engineering, 2017, 5: 3456-3464.
(17) Tianyi Jiang, Xiaoting Guo, Jinxing Yan, Yinxin Zhang, Yujiao Wang, Manman Zhang, Binbin Sheng, Cuiqing Ma, Ping Xu, Chao Gao*. A bacterial multidomain NAD-independent d-lactate dehydrogenase utilizes flavin adenine dinucleotide and Fe-S clusters as cofactors and quinone as an electron acceptor for d-lactate oxidization. Journal of Bacteriology, 2017, 199: 18.
(18) Yingxin Zhang#, Tianyi Jiang#, Binbin Sheng, Yangdanyu Long, Chao Gao*, Cuiqing Ma, Ping Xu. Coexistence of two d-lactate-utilizing systems in Pseudomonas putida KT2440. Environmental Microbiology Reports, 2016, 8: 699–707.
(19)Yujiao Wang, Yingxin Zhang, Tianyi Jiang, Jingjing Meng, Binbin Sheng, Chunyu Yang, Chao Gao*, Ping Xu, Cuiqing Ma*. A novel biocatalyst for efficient production of 2-oxo-carboxylates using glycerol as the cost-effective carbon source. Biotechnology for Biofuels, 2015, 8: 186.
(20) Zhaojuan Zheng, Binbin Sheng, Chao Gao, Haiwei Zhang, Tong Qin, Cuiqing Ma*, Ping Xu*. Highly stereoselective biosynthesis of (R)-α-hydroxy carboxylic acids through rationally re-designed mutation of d-lactate dehydrogenase. Scientific Reports, 2013, 3: 3401.
(21) Zhaojuan Zheng, Binbin Sheng, Cuiqing Ma*, Haiwei Zhang, Chao Gao, Fei Su, Ping Xu*. Relative catalytic efficiency of ldhL-and ldhD-encoded products is crucial for optical purity of lactic acid produced by Lactobacillus Strains. Applied and Environmental Microbiology, 2012, 78(9): 3480-3483.
教学论文
1. 盛彬彬,尹辉*,王卓娅,刘晓波. 国学“三十六计”融入微生物学与免疫学课程思政的思考,中国免疫学杂志,2024,40(01):174-177. (中文北大核心期刊.
2. 王卓娅, 邓祖军, 刘晓波, 李冰, 盛彬彬. 微生物学与免疫学虚实结合实验教学实践. 基础医学教育, 2020, 22: 909-911.